Our Research
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Active self-monitoring progress
In January 2020, A/Prof Anneke van der Walt was awarded a 3-year Trish Translational Research Project Grant titled, “Active self-monitoring to prospectively detect treatment failure and define subclinical progression trajectories in MS: The ACTIVE-MS Program”. Knowing as early as possible if a treatment for MS is keeping the disease under full control is important but…
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Clearance of myelin debris
An Incubator Grant titled, “TREM2 and clearance of myelin debris in MS” was awarded to Associate Professor Michael Buckland, following very generous support of donors at our Trish MS Winter Wonderland Ball. Multiple sclerosis (MS) is a disease in which the immune system attacks a protective sheath, called myelin, which covers nerves in the central…
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Role for EBV in MS
As a result of very generous support received at the Trish MS Winter Wonderland Ball, Stephen Schibeci was awarded an Incubator Grant titled, “How the EBV transcription factor EBNA2 regulates MS risk”, in lay terms, “A gene from a common virus changes the risk of Multiple Sclerosis”. The Incubator Grant looks at whether the Epstein-Barr…
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Strength to strength
The Trish MS Research Foundation funded the important work, ‘Enhancing brain activity to re-wrap nerve fibres’ of Associate Professor Kaylene Young at the Menzies Institute for Medical Research, Tasmania in 2017-2019. A/Prof Young’s inspiring research has gone from strength to strength. A/Prof Young, along with Professor Bruce Taylor at the Menzies Institute of Medical Research,…
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PrevANZ Update
The Trish MS Research Foundation contributed $200,000 to the world-first vitamin D MS Prevention Trial, PrevANZ. This study aims to see whether vitamin D supplementation can delay the onset of MS. In this gold standard double-blind placebo-controlled trial, people who had experienced their first MS-like episode and were diagnosed with CIS (clinically isolated syndrome) were…
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Incubator grant makes its mark
Following very generous support at the Trish Foundation’s 2018 Ball, an Incubator Grant titled “Developing methods to promote the creation of new myelin in MS”, was awarded to Associate Professor Anthony Don. A/Prof Don showed in laboratory models that S1P is essential for protecting the myelinating cells of the brain against damage and that loss…
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Important findings
Commencing January 2018, Professor Trevor Kilpatrick, The Florey Institute of Neuroscience and Mental Health, was awarded a 3-year Project Grant titled, “Enhancing Myelin Repair for Benefit in Multiple Sclerosis” to which the Trish MS Research Foundation contributed. Despite some unavoidable delays resulting from the extended Melbourne lockdown period, important findings have been made. In multiple…
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Understanding cellular mechanisms
Commencing 2019, A/Prof Simon Murray and Dr Jessica Fletcher, University of Melbourne, were awarded a 2-year Project Grant, fully funded by the Trish MS Research Foundation. The research is investigating promotion of myelin repair in the brain. Progress in the last calendar year has been limited due to the government enforced COVID-19 lockdown in Victoria.…
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Potential therapy for progressive forms of MS
Commencing 2018 the Trish Foundation began supporting a three-year MS Research Australia Project Grant awarded to Associate Professor Peter Crouch who began preclinical trials of a therapy for progressive multiple sclerosis at The University of Melbourne. Dr Crouch’s Co-investigators are Dr James Hilton, Dr Blaine Roberts, Dr Paul Donnelly and Dr Dominic Hare. A/Prof Crouch…
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Postgraduate Research Scholarship
Commencing January 2020, Dr Vivien Li, The Florey Institute of Neuroscience and Mental Health Victoria, was awarded a Postgraduate Research Scholarship over three years funded by the NHMRC with ‘top up’ funding by the Trish MS Research Foundation. The aim of the Project, titled “Towards developing dendritic cell therapy for multiple sclerosis based on promoting…