Our Research
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Which genes are involved in progressive MS?
Commencing 2018, Associate Professor Justin Rubio and his Co-investigators Associate Professor Stephen Leslie and Professor Michael Barnett were awarded a Project Grant funded by the Trish Foundation for two years investigating the DNA from single cells in the brain to better understand progressive MS. A/Prof Rubio and his team have isolated and analysed DNA from…
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Enhancing brain activity to re-wrap nerve fibres
In 2017 Associate Professor Kaylene Young was awarded a three-year Project Grant funded by the Trish MS Research Foundation. Over the course of this project, A/Prof Young and her team aimed to examine whether repetitive transcranial magnetic stimulation (rTMS) can induce cells to lay down new myelin and repair existing damage in three laboratory models…
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Promoting myelin repair by targeting Wnt signalling
The Trish MS Research Foundation is greatly honoured to have co-funded with the National Health and Medical Research Council, a National Health and Medical Research Council / MS Research Australia Betty Cuthbert Fellowship awarded to Dr David Gonsalvez, University of Melbourne. The Trish Foundation fully funded the MS Research Australia contribution. Dr Gonsalvez has made…
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Treating MS with cell and gene therapy
Dr Natalie Payne was awarded an Incubator Grant in 2018, fully funded by the Trish MS Research Foundation, titled, “Treating MS with cell and gene therapy”. Dr Payne and her team have created a specially designed cell that produces a drug that targets a pathway associated with the progression of MS. The drug blocks an…
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Encouraging the natural repair abilities of immune cells
Dr Claire McCoy was awarded an Incubator Grant in 2018, fully funded by the Trish MS Research Foundation, titled, “Encouraging the natural repair abilities of immune cells”. Dr McCoy and her team have successfully created a laboratory model of MS in which the miR-155 is selectively absent in macrophage cells. Macrophages move in large numbers…
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The role of Vitamin D related genes in MS
In 2016, Dr Lawrence Ong was awarded a Betty Cuthbert Postgraduate Scholarship co-funded by the National Health and Medical Research Council and MS Research Australia, with the MS Research Australia contribution provided with full funding support from the Trish MS Research Foundation. The Trish Foundation was honoured to be co-funding this important Research Project with…
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Does stimulating brain activity improve myelin repair?
Dr Tobias Merson, Monash University Victoria, was awarded a Project Grant over 2017-2018, funded by the Trish Multiple Sclerosis Research Foundation, his Co-Investigator being Dr Stanislaw Mitew. Dr Merson’s team have shown that increasing the electrical activity of nerve fibres in brain tissue that is not affected by MS enhances the laying down of myelin…
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Findings attract exciting international collaborations
The Trish Foundation is supporting a three-year MS Research Australia Project Grant awarded to A/Prof Peter Crouch who will begin preclinical trials of a therapy for progressive multiple sclerosis at The University of Melbourne. Dr Crouch’s Co-investigators are Dr James Hilton, Dr Blaine Roberts, Dr Paul Donnelly and Dr Dominic Hare. Unfortunately, there are very…
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What Role do Natural Killer Cells play in MS?
The Trish MS Research Foundation has part funded an MS Research Australia Project Grant, ‘What Role do Natural Killer Cells play in MS?’, the Chief Investigator being Dr Fiona McKay, Westmead Institute for Medical Research, NSW. Natural killer (NK) cells are responsible for killing harmful cells in the body. This includes the body’s own cells…
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Development of iPad Tool
Dr Joshua Barton was awarded a Postgraduate Scholarship titled, “Subclinical disease progression and repair in multiple sclerosis: novel application of standardised functional visual biomarkers”, which was fully funded by the Trish MS Research Foundation. The current methods available to clinicians and researchers to measure the progression of disease and disability in people with MS are…