Promoting Remyelination

Commencing January 2023, Professor Paul Stupple and Dr Steven Petratos, Monash University, were awarded a 2-year Trish Translational Research Project Grant titled, “Development of Small Molecules to Promote Remyelination in Multiple Sclerosis”.

Professor Stupple and Dr Petratos are working on developing a small molecule-based treatment to reverse progressive MS through promoting remyelination of neurons.  They are aiming to carry out translational research that will potentially lead to clinical trials of a new class of molecules to treat people living with progressive MS. Their academic research is targeting immature oligodendrocytes that can repair damaged regions of the brain from MS attacks. This new class of molecules may activate these cells to mature and produce myelin.

Professor Stupple and Dr Petratos are making great progress with their tremendous work, however specific details are confidential for now.